A scientific update on the gut microbiome presented by Professor David Cameron-Smith
The human gut microbiome is a dynamic population of trillions of bacteria that exist in the human large intestine. Rapid progress has been made in the past decade to increase the understanding of the importance of the gut microbiome in mediating health impact throughout the host. This includes establishing and maintaining immune homeostasis, with bioactive metabolites (including vitamins) and digesting nutrients collectively impacting on disease risk. As diet is the most important determinant of microbiome composition and function, continued emphasis should be given to effective strategies to ‘feed our microbiome’. This includes dietary patterns that are plant-focused, with the complex carbohydrates and polyphenolic compounds being major regulators of the microbiome population.
Learn about:
1. How the gut microbiome plays a crucial role in lifelong health by regulating metabolic functions, immune responses, and disease risk through its interactions with diet and host cells.
2. Early life factors, including birth modality and breastfeeding, significantly influence the composition and stability of the gut microbiome, which in turn affects long-term health outcomes.
3. Modern dietary patterns, particularly rich in ultra-processed foods, can negatively impact gut microbiome diversity and function, contributing to chronic diseases like cardiovascular disease and diabetes.
Professor David Cameron Smith is a globally recognised clinical scientist, with 25 years’ experience in human nutrition research. His scientific research includes leading more than 20 clinical trials and publishing over 300 scientific papers. His focus is on the biochemical, genetic, microbiome mechanisms that connect dietary intake with health outcomes, with a focus on ageing, muscles and cardiovascular health.
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